biophysics_fitting ❭ ephys ❭ STEP_fast_ahp_depth

STEP_fast_ahp_depth

biophysics_fitting.ephys.STEP_fast_ahp_depth(t, v, thresh=None, time_scale=5, start=1)

Computes the average depth of the fast afterhyperpolarization (fAHP) of a voltage trace for a step stimulus.

The fAHP is computed as the deepest point right after (i.e. within timescale) the spike.

Note

If two consecutive spikes are less than timescale apart, the fAHP is computed as simply minimum between the first spike and the next spike, and there is no difference between fast and slow AHP.

Parameters:

  • t (numpy.ndarray) – Array of time values.

  • v (numpy.ndarray) – Array of voltage values.

  • thresh (float, optional) – Voltage threshold for spike detection. Defaults to None.

  • time_scale (float, optional) – Time scale in milliseconds. Defaults to 5.

  • start (int) – Index of the first AP to be considered. Defaults to 1: Omit the first AP with index 0.

Returns:

Depth of the fAHP.

Return type:

float