STEP_slow_ahp_depth¶

biophysics_fitting.ephys.STEP_slow_ahp_depth(t, v, thresh=None, time_scale=5, start=1)¶

Computes the average depth of the slow afterhyperpolarization (sAHP) of a voltage trace for a step stimulus.

The sAHP is computed as the deepest point between time_scale after the spike and the next spike.

Note

If two consecutive spikes are less than time_scale apart, the sAHP is computed as the minimum between the first spike and the next spike, and there is no difference between fast and slow AHP.

Parameters:¶

t : numpy.ndarray¶

Array of time values.

v : numpy.ndarray¶

Array of voltage values.

thresh : float, optional¶

Voltage threshold for spike detection. Defaults to None.

time_scale : float, optional¶

Time scale in milliseconds. Defaults to 5 ms.

start : int¶

Index of the first AP to be considered. Defaults to 1: Omit the first AP with index 0.

Returns:¶

Depth of the sAHP.

Return type:¶

float